Current use and advances in vasopressors and inotropes support in shock

Philip Panagiotis Manolopoulos, Ioannis Boutsikos, Panagiotis Boutsikos, Nicoletta Iacovidou, Konstantinos Ekmektzoglou


Fluid resuscitation, vasopressors and inotropes are the first line medication for the different types of shock due to their mechanism of action and their well-established clinical outcome. However, as experimental research and clinical trials are constantly being published, new suggestions appear regarding alterations and novelties in the use of these medications in the management of shock. The purpose of this review is to address both the current use of vasopressors and inotropes support in shock (thereby, offering a concise review of the pathophysiology behind shock alongside a helpful clinical reference tool for the emergency physician) as well as to describe recent advances (both experimental and clinical) that could hold a critical role for the near future regarding patient management.