Cons: should universal decolonization be performed routinely for critically ill patients?

The decolonization strategy is gradually applied in intensive care unit (ICU) through the years. Theoretical basis for supporting the strategy is based upon the notion that decolonization reduces the chance of infection. Therefore, recommendation of taking universal decolonization program was proposed in some countries. Nevertheless, the evidence to support universal decolonization strategy in ICU is still lacking and adverse effects related to universal decolonization need serious concern.