Luigi Tritapepe, MD

Department of Cardiological, Respiratory, Nephrology, Anesthesiology and Geriatric Sciences, Policlinico Umberto I Hospital, Sapienza University of Rome, Rome, Italy

Prof. Tritapepe is an Associate Professor of Anesthesia and intensive Care Medicine at the University of Rome (Sapienza University of Rome) and Anesthesiologist and Intensivist in the Department of Heart and Great Vessels at Sapienza University and Policlinico Umberto I Hospital in Rome. He obtained his Anesthesiological degree at the University of Rome in 1988.

He was a member of the European Society of Intensive Care Medicine (ESICM), and of the European Society of Anaesthesiology (ESA). He is an active member of the Italian Society of Anesthesia (SIAARTI).

Prof. Tritapepe has signed more than 200 original articles, some 30 book chapters and review articles, 70 original abstracts. He is member of the editorial boards of some journals, and reviewer of Minerva Anestesiologica (from 2012), BMC Anesthesiology (from 2014), Intensive Care Medicine (2015), British Journal of Anaesthesia (2016), Turkiye Klinikleri Journal of Case Reports (2018), Journal of Emergency and Critical Care Medicine (from 2017), Plos One (from 2013), Clinical Pharmacology: Advances and Applications (2015-2016), Turkish Journal of Anaesthesiology and Reanimation (from 2015), Mediators of Inflammation (2016), International Journal of Clinical Transfusion Medicine (2016), Scientific Reports (from 2014), BMC Emergency Medicine (from 2014), Medical Research Archives (2015), American Heart Journal (2015), Therapeutic Apheresis and Dialysis (2014-2015), Journal of Anesthesiology (from 2014), British Medical Journal (2013-2015), Computer Methods and Programs in Biomedicine (2013-2014), Critical Care Medicine (2013), Medical Science Monitor (2013-2014), American Journal of Respiratory and Critical Care Medicine (2012), Perfusion (2013), International Journal of Cardiology (2013-2016).

Main studies focused on anesthesia in cardiac surgery, pulmonary hypertension, role of opioids and induction agents in cardiac anesthesia, aortic dissection, stun and myocardial ischemic preconditioning, cardiac protection. For about 15 years, marked interest in the molecular mechanisms of pharmacological cardioprotection, studying in vivo the protective action of halogenated anesthetics administered during cardiac surgery and especially during extracorporeal circulation. Interest then deepened in vitro, through the study of the pharmacological action of levosimendan on isolated atrial myocardial cells. Study results then transferred in vivo through levosimendan administration prior to extracorporeal circulation, resulting in less troponin release and favorable outcomes for inotropic use. Study of the mechanisms of aortic dissection and of the containment of bleeding in type A dissection by using activated factor VII. Research of favorable actions on the heart rate of ivabradine, able to counteract the toxic effects of catecholamines infused in the syndrome of low cardiac output.

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