TY  - JOUR
AU  - Ho, Kwok M.
PY  - 2018
TI  - Importance of the baseline risk in determining sample size and power of a randomized controlled trial
JF  - Journal of Emergency and Critical Care Medicine; Vol 2 (September 2018): Journal of Emergency and Critical Care Medicine
Y2  - 2018
KW  - 
N2  - Accurate estimation of adequate sample size to reduce the possibility of a type II error (false negative) is important in planning a randomized controlled trial (RCT). It becomes apparent that many recent critical care trials could not reject the null hypothesis; so much so that the proportion of clinical trials rejecting the null hypothesis on crude mortality outcome was close to the conventional acceptable type I error (5%) (1).
UR  - https://jeccm.amegroups.org/article/view/4550