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Importance of the baseline risk in determining sample size and power of a randomized controlled trial

   
@article{JECCM4550,
	author = {Kwok M. Ho},
	title = {Importance of the baseline risk in determining sample size and power of a randomized controlled trial},
	journal = {Journal of Emergency and Critical Care Medicine},
	volume = {2},
	number = {9},
	year = {2018},
	keywords = {},
	abstract = {Accurate estimation of adequate sample size to reduce the possibility of a type II error (false negative) is important in planning a randomized controlled trial (RCT). It becomes apparent that many recent critical care trials could not reject the null hypothesis; so much so that the proportion of clinical trials rejecting the null hypothesis on crude mortality outcome was close to the conventional acceptable type I error (5%) (1).},
	issn = {2521-3563},	url = {https://jeccm.amegroups.org/article/view/4550}
}