Association and dissociation of microcirculation and macrocirculation in critically ill patients with shock

Yu-Chang Yeh, Ching-Tang Chiu


Early goal-directed therapy with maintenance of adequate central venous pressure (CVP), mean arterial pressure (MAP), and central venous oxygen saturation (ScvO2) fails to improve survival (1-3) in patients with shock, which emphasizes the fact that normal values of macrocirculation parameters may be inadequate to prevent shock.