Beware of broad-spectrum generalizations: ceftazidime-avibactam compared to meropenem for the treatment of gram-negative pneumonia

Nosocomial pneumonia remains a serious challenge to modern healthcare and accounts for a substantial proportion of healthcare associated infections. Frequently, nosocomial pneumonia, and in particular ventilator-associated pneumonia, is caused by multi-drug resistant (MDR) Gram-negative organisms, leaving clinicians few effective therapeutic options.